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Registro Completo |
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Biblioteca(s): |
Embrapa Meio Ambiente. |
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Data corrente: |
20/12/2023 |
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Data da última atualização: |
20/12/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
JONSSON, C. M.; QUEIROZ, S. C. do N. de. |
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Afiliação: |
CLAUDIO MARTÍN JONSSON, LABORATÓRIO DE AQUICULTURA E ECOTOXICOLOGIA, EMBRAPA MEIO AMBIENTE (EMBRAPA ENVIRONMENT), RODOVIA SP-340, KM 127.5, TANQUINHO VELHO, JAGUARIÚNA 13918-110, SP, BRAZIL; SONIA CLAUDIA DO NASCIMENTO DE QUEIROZ, LABORATÓRIO DE RESÍDUOS E CONTAMINANTES, EMBRAPA MEIO AMBIENTE (EMBRAPA ENVIRONMENT), RODOVIA SP-340, KM 127.5, TANQUINHO VELHO, JAGUARIÚNA 13918-110, SP, BRAZIL. |
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Título: |
Concepts on accumulation of pesticides and veterinary drugs in fish: a review with emphasis in tilapia. |
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Ano de publicação: |
2023 |
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Fonte/Imprenta: |
Animals, v. 13, n. 17, article 2748, 2023. |
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ISSN: |
2076-2615 |
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DOI: |
https://dx.doi.org/10.3390/ani13172748 |
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Idioma: |
Inglês |
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Notas: |
Disponível em: https://doi.org/10.3390/ani13172748. Acesso em |
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Conteúdo: |
Abstract: The quality of the aquatic environment can be compromised by the practice of intensive use of pesticides in agriculture and by the misuse of veterinary drugs. Therefore, organisms that live in aquatic ecosystems may be affected due to the presence of these chemicals, through runoff, leaching and other processes. Exposure of aquatic organisms to these xenobiotics could pose health risks. Consequently, there is a growing interest in predicting the bioaccumulation of these substances in aquatic biota from experiments conducted under laboratory conditions. Studies on fish have been performed due to its importance as human food and their wide distribution in most of the aquatic environment. Thus, this article reviews the concepts on determining the accumulation of pesticides and veterinary drugs in fish. The risk regarding the consumption of fish containing residues of these chemical agents, the acceptable daily intake, the testing protocols and the analytical techniques used to determine the residues of these substances in fish tissues are discussed. An emphasis on studies involving tilapia as the test organism was included because, according to Food and Agricultural Organization (FAO), this species is one of the most cultivated in the world. |
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Palavras-Chave: |
Bioconcentration factor; Contaminants. |
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Thesagro: |
Agrotóxico; Medicamento; Resíduo Quimico; Tilápia; Toxicologia; Toxicologia de Alimento. |
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Thesaurus Nal: |
Bioaccumulation; Bioaccumulation factor; Pesticides; Tilapia (common name); Veterinary drugs. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1160112/1/Jonsson-Concepts-accumulation-2023.pdf
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Marc: |
LEADER 02286naa a2200325 a 4500
001 2160112
005 2023-12-20
008 2023 bl uuuu u00u1 u #d
022 $a2076-2615
024 7 $ahttps://dx.doi.org/10.3390/ani13172748$2DOI
100 1 $aJONSSON, C. M.
245 $aConcepts on accumulation of pesticides and veterinary drugs in fish$ba review with emphasis in tilapia.$h[electronic resource]
260 $c2023
500 $aDisponível em: https://doi.org/10.3390/ani13172748. Acesso em
520 $aAbstract: The quality of the aquatic environment can be compromised by the practice of intensive use of pesticides in agriculture and by the misuse of veterinary drugs. Therefore, organisms that live in aquatic ecosystems may be affected due to the presence of these chemicals, through runoff, leaching and other processes. Exposure of aquatic organisms to these xenobiotics could pose health risks. Consequently, there is a growing interest in predicting the bioaccumulation of these substances in aquatic biota from experiments conducted under laboratory conditions. Studies on fish have been performed due to its importance as human food and their wide distribution in most of the aquatic environment. Thus, this article reviews the concepts on determining the accumulation of pesticides and veterinary drugs in fish. The risk regarding the consumption of fish containing residues of these chemical agents, the acceptable daily intake, the testing protocols and the analytical techniques used to determine the residues of these substances in fish tissues are discussed. An emphasis on studies involving tilapia as the test organism was included because, according to Food and Agricultural Organization (FAO), this species is one of the most cultivated in the world.
650 $aBioaccumulation
650 $aBioaccumulation factor
650 $aPesticides
650 $aTilapia (common name)
650 $aVeterinary drugs
650 $aAgrotóxico
650 $aMedicamento
650 $aResíduo Quimico
650 $aTilápia
650 $aToxicologia
650 $aToxicologia de Alimento
653 $aBioconcentration factor
653 $aContaminants
700 1 $aQUEIROZ, S. C. do N. de
773 $tAnimals$gv. 13, n. 17, article 2748, 2023.
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Registro original: |
Embrapa Meio Ambiente (CNPMA) |
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Registro Completo
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Biblioteca(s): |
Embrapa Meio Ambiente. |
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Data corrente: |
17/07/2023 |
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Data da última atualização: |
27/07/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 2 |
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Autoria: |
GOMES, T. C.; CONRADO, R.; OLIVEIRA, R. C. de; SELARI, P. J. R. G.; MELO, I. S. de; ARAÚJO, W. L.; MARIA, D. A.; SOUZA, A. O. de. |
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Afiliação: |
TAINAH COLOMBO GOMES, INSTITUTO BUTANTAN; RAFAEL CONRADO, INSTITUTO BUTANTAN; RODRIGO CARDOSO DE OLIVEIRA, UNIVERSIDADE DE SÃO PAULO; PRISCILA JANE ROMANO GONÇALVES SELARI, INSTITUTO FEDERAL GOIANO; ITAMAR SOARES DE MELO, CNPMA; WELINGTON LUIZ ARAÚJO, UNIVERSIDADE DE SÃO PAULO; DURVANEI AUGUSTO MARIA, INSTITUTO BUTANTAN; ANA OLÍVIA DE SOUZA, INSTITUTO BUTANTAN. |
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Título: |
Effect of Monocerin, a fungal secondary metabolite, on endothelial cells. |
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Ano de publicação: |
2023 |
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Fonte/Imprenta: |
Toxins v. 15, n. 5, article 344, 2023. |
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ISSN: |
2072-6651 |
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DOI: |
https://doi.org/10.3390/toxins15050344 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: This study reports the isolation and identification of the endophytic fungus Exserohilum rostratum through molecular and morphological analysis using optical and transmission electron microscopy (TEM), as well as the procurement of its secondary metabolite monocerin, an isocoumarin derivative. Considering the previously observed biological activities of monocerin, this study was performed on human umbilical vein endothelial cells (HUVECs) that are widely used as an in vitro model for several different purposes. Important parameters, such as cell viability, senescence-associated ?-galactosidase, cellular proliferation by using 5(6)-carboxyfluorescein diacetate N-succinimidyl ester (CFSE), apoptosis analysis with annexin, cellular morphology through scanning electron microscopy (SEM), and laser confocal analysis were evaluated after exposing the cells to monocerin. After 24 h of exposure to monocerin at 1.25 mM, there was more than 80% of cell viability and a low percentage of cells in the early and late apoptosis and necrosis. Monocerin increased cell proliferation and did not induce cell senescence. Morphological analysis showed cellular integrity. The study demonstrates aspects of the mechanism of action of monocerin on endothelial cell proliferation, suggesting the possibility of its pharmaceutical application, such as in regenerative medicine. |
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Palavras-Chave: |
Monocerin. |
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Thesagro: |
Caatinga; Cróton; Fungo. |
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Thesaurus NAL: |
Cell senescence; Cell viability; Endophytes; Exserohilum; Fungi; Medicinal fungi; Secondary metabolites. |
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Categoria do assunto: |
S Ciências Biológicas |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1154958/1/Melo-Effect-monocerin-2022.pdf
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Marc: |
LEADER 02351naa a2200361 a 4500
001 2154958
005 2023-07-27
008 2023 bl uuuu u00u1 u #d
022 $a2072-6651
024 7 $ahttps://doi.org/10.3390/toxins15050344$2DOI
100 1 $aGOMES, T. C.
245 $aEffect of Monocerin, a fungal secondary metabolite, on endothelial cells.$h[electronic resource]
260 $c2023
520 $aAbstract: This study reports the isolation and identification of the endophytic fungus Exserohilum rostratum through molecular and morphological analysis using optical and transmission electron microscopy (TEM), as well as the procurement of its secondary metabolite monocerin, an isocoumarin derivative. Considering the previously observed biological activities of monocerin, this study was performed on human umbilical vein endothelial cells (HUVECs) that are widely used as an in vitro model for several different purposes. Important parameters, such as cell viability, senescence-associated ?-galactosidase, cellular proliferation by using 5(6)-carboxyfluorescein diacetate N-succinimidyl ester (CFSE), apoptosis analysis with annexin, cellular morphology through scanning electron microscopy (SEM), and laser confocal analysis were evaluated after exposing the cells to monocerin. After 24 h of exposure to monocerin at 1.25 mM, there was more than 80% of cell viability and a low percentage of cells in the early and late apoptosis and necrosis. Monocerin increased cell proliferation and did not induce cell senescence. Morphological analysis showed cellular integrity. The study demonstrates aspects of the mechanism of action of monocerin on endothelial cell proliferation, suggesting the possibility of its pharmaceutical application, such as in regenerative medicine.
650 $aCell senescence
650 $aCell viability
650 $aEndophytes
650 $aExserohilum
650 $aFungi
650 $aMedicinal fungi
650 $aSecondary metabolites
650 $aCaatinga
650 $aCróton
650 $aFungo
653 $aMonocerin
700 1 $aCONRADO, R.
700 1 $aOLIVEIRA, R. C. de
700 1 $aSELARI, P. J. R. G.
700 1 $aMELO, I. S. de
700 1 $aARAÚJO, W. L.
700 1 $aMARIA, D. A.
700 1 $aSOUZA, A. O. de
773 $tToxins$gv. 15, n. 5, article 344, 2023.
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Embrapa Meio Ambiente (CNPMA) |
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